Semaglutide (Ozempic, Wegovy): Evidence and What Users Report

Semaglutide didn’t stop my hunger. It just made eating too much feel miserable. Tirzepatide was completely differen, just 0 interest.. Most of my 57-pound loss happened after switching.

Terrified of starting Reta. I follow all the X peptide accounts but most are already in shape while I need to lose 60+ lbs. so unsure where to start at or expect. Tried lira and semaglutide years ago with no success.

Everyone told me GLP-1s make you sluggish and sick. Reta did the opposite. Wired me. 2am, eyes open, heart going, not anxious exactly just switched on with nowhere to put it. It's not the sedating misery people describe with sema. It's a stimulant wearing a weight-loss drug's clothes. Nobody sleeps and nobody says so.

didn't take sema for my heart. might've been the best thing I ever did for it anyway. 17,000 people, no diabetes, 20% fewer heart attacks and strokes and it held whether or not you lost much weight, so it's not just the scale doing the work. my dad died at 61 of a heart attack. I take mine and I think about him. that's the whole confession.

nausea. vomiting. constipation. burping I won't get into. 65% of people on sema get some kind of gut disaster and I got the full menu. lost the weight though. spent month one on the bathroom floor earning it.

nobody warned me my skin would feel like it was on fire. pins and needles, then a burning nobody could see. I thought I was having a stroke. turns out on the top dose it happens to about 1 in 5 people, it's the glucagon part of reta doing something to your nerves, and it's the one side effect tirz and sema don't give you. I was in the 20%. I dropped the dose and it faded. wish the people posting their weight loss numbers mentioned this part even once.

stacked reta, sema, AND tirz at once. all three. do not do this. the weight fell off and so did my ability to function, couldn't eat, couldn't hydrate, heart going crazy. it's not three times the results, it's three times the damage to the same system. pick one. I'm serious. My wife and kids would kill me

Got the Ozempic zombie face, why was this allowed? any advice?

My dad died at 50 from obesity, and I saw myself going down the same path so I started tirzepatide then moved to semaglutide. My dad would be proud, keep hearing about Reta but it also seems much riskier

Switched from sema to tirz six weeks ago, down another 11. the thing i can't get over is I used to plan my whole day around lunch and now I forget to eat it , not in a dramatic way. I just look and it's 4pm and hunger is no where to be seen

lost 40 lbs on sema and got pregnant for the first time in 8 years of trying, my fertility doctor spent a decade and more than a fortune... totally crazy that a "weight loss" drug did it by accident

A growth on my left side, the hydrocele, had been bothering me for a long time. It had swollen to roughly the size of a small plum, big enough that doctors were talking surgery. After I started Ozempic it slowly came down on its own over a couple of months until it was back to normal. I actually didn't realize how much it had settled until I went in for an MRI on a fatty lump on my thigh, which had only become visible once I lost weight. The scan happened to capture the old swelling too and graded it as nothing more than minor.

quit sema after 11 months and 65 lbs because I thought I'd "learned new habits." the food noise was back in 3 weeks and it came back LOUDER than before I started. gained 20 in two months. it's not a course you finish, it's a tool you keep using. wish someone had been honest with me about that before I started.

took semaglutide for 14 months. gained it all back in 4. nobody warned me the (off ramp) was a cliff from fat to pretty and back to fat & ugly

things i learned the hard way on retatrutide: the nausea peaks at week 3 not week 1 alcohol becomes literally toxic, one beer = food poisoning sulfur burps mean you're titrating too fast the "ozempic face" thing is real and arrives at month 4 nobody tells you any of this until you post about it

So my wife starts sema. Lowest dose they make, two weeks in she pours some wine, takes one sip, and just... puts it down. Says it tastes weird. That was four months ago. She hasn't touched alcohol since, Doctor didn't tell us GLP-1s did this. Apparently they hit the same dopamine pathways as addiction meds. Rewired her entire brain

Semaglutide gave me the worst hair loss of my life :( Lost a third of my hair density in 5 months. Dr said it was the rapid weight loss, not the drug but switched to tirzepatide at a slower titration and my hair kinda grew back so idk

Semaglutide cured my type 2 diabetes, full remission

I started semaglutide three weeks after my daughter's wedding photos. I got angry looking at them. Not because of her but because I couldn't find myself in the background. I had become a shape I didn't recognize. I lost 52 pounds. At her baby shower, my granddaughter-to-be will meet a grandmother who exists. That's what I paid for

Semax 1 mg SubQ in the morning gives a nice mental boost, clarity and crisp focus.