Data report
Tirzepatide side effects: what users report in 93 anonymous confessions
Counts from published confessions tagged Tirzepatide. What users report about tirzepatide side effects is read off the published text. The archive has no side-effect column, so each figure is a phrase match. This is not a clinical rate, and it is not medical advice.
Headline stats
What users report in 93 published anonymous confessions tagged tirzepatide: 11 (11.8%) mention heart rate or palpitations. 10 name a tirzepatide milligram figure, and 5 state a pound loss with lost, down, or dropped. Data through 18 October 2026. Figures on this page are phrase matches over anonymous published stories, not clinical incidence. This is not a dosing recommendation.
- Published confessions
- 93
- Most mentioned side-effect phrase
- Heart rate or palpitations · 11 (11.8%)
- Confessions with any side-effect phrase
- 27
- Confessions naming a figure
- 10
- Most named figure
- 5 mg · 4 confessions
- Confessions naming a week
- 12
- Confessions naming a month
- 16
- Confessions stating a pound loss
- 5 · median 50 lb
93 published confessions, 21 May 2026 through 18 October 2026 (UTC). 27 mention at least one side-effect phrase in the lexicon below.
Side effects mentioned
Share of published tirzepatide confessions whose text matches the phrase. One confession can match more than one row. A denial next to the phrase is not counted. What users report is a phrase, not a diagnosis.
| Phrase | Confessions | % | Share of corpus |
|---|---|---|---|
| Heart rate or palpitations | 11 | 11.8% | |
| Anxiety or panic | 5 | 5.4% | |
| Burping | 4 | 4.3% | |
| Insomnia or poor sleep | 3 | 3.2% | |
| Libido | 3 | 3.2% | |
| Low mood or anhedonia | 3 | 3.2% | |
| Dizziness | 2 | 2.2% | |
| Hair shedding | 2 | 2.2% | |
| Diarrhea | 1 | 1.1% | |
| Fatigue or exhaustion | 1 | 1.1% | |
| Muscle loss | 1 | 1.1% | |
| Reflux or heartburn | 1 | 1.1% | |
| Vomiting | 1 | 1.1% | |
| Constipation | 0 | 0% | |
| Cramps | 0 | 0% | |
| Headache | 0 | 0% | |
| Injection-site reaction | 0 | 0% | |
| Nausea | 0 | 0% | |
| Sensitive skin | 0 | 0% |
Also written, not scored as a side effect
Appetite and hunger are the change these confessions usually set out to describe. “No side effects” is a phrase about the absence of effects.
| Phrase | Confessions | % | Share of corpus |
|---|---|---|---|
| Appetite, hunger, or food noise | 9 | 9.7% | |
| "No", "zero", or "minimal" side effects | 0 | 0% |
Reported doses
A milligram figure counts when it is written next to tirzepatide, tirz, Mounjaro, or Zepbound. Figures next to another compound, a price, or a vial size are left out, as are amounts above 20 mg. Each distinct figure counts once per confession. Figures that appear in only one confession are omitted from the table.
This is not a dosing recommendation.
10 of 93 confessions (10.8%) name at least one such figure. 4 other figures appear in a single confession and are not listed.
| Figure | Confessions | % of corpus | % of confessions with a figure |
|---|---|---|---|
| 5 mg | 4 | 4.3% | 40% |
| 1 mg | 2 | 2.2% | 20% |
| 2.5 mg | 2 | 2.2% | 20% |
| 10 mg | 2 | 2.2% | 20% |
Timelines
Week numbers and month numbers are counted separately. A month is not turned into four weeks. A confession that names two different weeks can appear in two week rows.
Weeks (12 confessions name a week)
| Range | Confessions | % | Share of corpus |
|---|---|---|---|
| 1–4 weeks | 4 | 4.3% | |
| 5–8 weeks | 6 | 6.5% | |
| 9–12 weeks | 1 | 1.1% | |
| 13–26 weeks | 1 | 1.1% | |
| 27 weeks or more | 0 | 0% |
Months (16 confessions name a month)
| Range | Confessions | % | Share of corpus |
|---|---|---|---|
| 1–2 months | 3 | 3.2% | |
| 3–5 months | 6 | 6.5% | |
| 6–11 months | 6 | 6.5% | |
| 12 months or more | 2 | 2.2% |
Outcomes written in the text
A weight figure counts only when it follows lost, down, or dropped. Kilograms stay in kilograms. A figure next to semaglutide, retatrutide, Ozempic, Wegovy, or Rybelsus is left out. Start weight and end weight with no unit are left out. What users report is not a result to expect.
Pound losses: 5 confessions. Median 50 lb, range 35–80 lb. Kilogram losses: 3 confessions. Median 17 kg, range 17–22 kg.
| Range | Confessions | % | Share of corpus |
|---|---|---|---|
| Under 10 lb | 0 | 0% | |
| 10–19 lb | 0 | 0% | |
| 20–39 lb | 1 | 1.1% | |
| 40–59 lb | 3 | 3.2% | |
| 60 lb or more | 1 | 1.1% |
| Phrase | Confessions | % | Share of corpus |
|---|---|---|---|
| Says they stopped, quit, or came off tirzepatide | 2 | 2.2% |
Related confessions
The newest published confession for each of the most mentioned side effects. The full archive is on the tirzepatide page.
Heart rate or palpitations
Was on Tirz. Shifted to Reta. Tanked my HRV and RHR shot off more than 18-20pts. Stalled. However a Dexa scan revealed massive fat loss, especially visceral fat. However given a…#773 · 7 October 2026
Anxiety or panic
Here’s how trying to finish my weight loss went: Ozempic: lost 50 pounds. Tirzepatide: lost another 67. Fourteen pounds left to goal. Switched to retatrutide. Three months later…#668 · 20 September 2026
Burping
Was on Tirz. Shifted to Reta. Lost considerable weight. Had Sleep Apnea and had to use CPAP. GLPs made CPAP redundant. However I tried using Cpap for deep sleep and recovery. Wh…#774 · 7 October 2026
Insomnia or poor sleep
I think Tirz is Objectively better than Reta. Both compounds are amazing, but Tirz wins the overall head to head and it’s not really close. Reta = A Tier Tirz = S Tier The reaso…#470 · 16 August 2026
Libido
I lost 35 lbs on tirzepatide in the past 4 months but it has really taken it out of me. I told my doc that my libido is absolutely in the crapper and they put me on CJC-1295 / I…#422 · 8 August 2026
How to cite
The sentence in the summary is the citable line. The block below is HTML; it uses the same numbers as this page.
<blockquote cite="https://www.peptideconfessions.com/reports/tirzepatide-side-effects"> <p>What users report in 93 published anonymous confessions tagged tirzepatide: 11 (11.8%) mention heart rate or palpitations. 10 name a tirzepatide milligram figure, and 5 state a pound loss with lost, down, or dropped. Data through 18 October 2026. Figures on this page are phrase matches over anonymous published stories, not clinical incidence. This is not a dosing recommendation.</p> <footer>Source: <a href="https://www.peptideconfessions.com/reports/tirzepatide-side-effects">Peptide Confessions, tirzepatide side-effect report</a>. Anonymous published confessions through 18 October 2026. Not medical advice. This is not a dosing recommendation.</footer> </blockquote>
Questions
- What tirzepatide side effects do users report?
- A confession counts when its text matches the shared phrase list (for example nausea, constipation, heart rate, palpitations). A denial in the preceding words ("no nausea") does not count. The side-effect phrase users report most often is heart rate or palpitations: 11 of 93 confessions (11.8%). Silence is not recorded: people who never name an effect are in the denominator only.
- How many confessions are in this tirzepatide count?
- 93 published confessions are tagged tirzepatide. The site has no accounts, so this is a count of submissions, not a verified count of distinct people. Published dates run from 21 May 2026 through 18 October 2026.
- Are these tirzepatide doses a recommendation?
- This is not a dosing recommendation. 10 of 93 confessions write a figure next to tirzepatide, tirz, Mounjaro, or Zepbound. Figures are kept when they sit near that name, and dropped when they sit near another compound, a price, or a vial size. One distinct figure counts once per confession. The figure named in the most confessions is 5 mg (4 confessions).
- Do these percentages show what tirzepatide causes?
- A percentage is the share of published confessions that used a phrase. Figures on this page are phrase matches over anonymous published stories, not clinical incidence.
- Why are weeks and months separate?
- 12 confessions write an explicit week number, and 16 write an explicit month number. Months are not converted into weeks. A confession can land in more than one bucket when it names more than one number.
- How is weight loss counted?
- 5 confessions contain a pound figure written with lost, down, or dropped. 3 do the same in kilograms. Kilograms are not converted to pounds. A figure whose nearby subject is semaglutide, retatrutide, or a brand name for those is left out. Start-and-end weights with no unit word are left out. The median is the middle value of the figures that remain. What users report here is not a result to expect.
- Is tirzepatide the same as Mounjaro or Zepbound?
- Yes. Mounjaro and Zepbound are brand names for tirzepatide, and many writers call it tirz. This report counts all four names. Compounded and grey-market tirzepatide are described in the same confessions and are not separated.
- Where are the full tirzepatide stories?
- On the tirzepatide hub, which also covers stalls, regain after stopping, and switches to retatrutide. The comparisons are semaglutide vs tirzepatide and retatrutide vs tirzepatide.
Methodology
Cohort: confessions with status published and a Tirzepatide tag. Data through 18 October 2026. The page is cached and regenerated about once an hour from that query.
There is no structured field for side effect, use, dose, week, or outcome. Matches are case-insensitive phrases. A phrase that nobody used stays in the table at zero. “Tired”, “sleep”, “heart”, and “skin” alone are not scored; those words show up in stories that are not about a side effect.
Figures on this page are phrase matches over anonymous published stories, not clinical incidence.
This is not a dosing recommendation. Doses are not a protocol. Weight figures, where this page shows them, are not a result you should expect. Nothing on this page is a finding from a trial.
Editorial rules for what gets published are on the methodology page. Vendor names are not repeated here.