GHK-Cu Before and After: What 65 Users Report

What is GHK-Cu?

GHK-Cu is a copper-binding tripeptide, glycyl-L-histidyl-L-lysine bound to copper. It is present in human plasma. People also write it as GHKCU, or call it a copper peptide. It is not an approved drug.

On this site it shows up in skin notes, hair notes, and injection-site complaints. Many of those confessions also name a GLP-1, BPC-157, or a blend. The line above is the molecule. The rest is what people wrote.

What do people report GHK-Cu doing?

Skin is the most common claim, and it is not universal. #283 says a dermatologist complimented their skin and asked about the routine. #221 describes airbrushed-looking skin and a faded chin scar at three weeks, and injects it. #292 almost quit at three weeks because the skin looked worse, then says week six turned and week twelve the skin was denser. #386 at one month: softer forehead lines, faster nails, hair that seems to be growing faster. #75 says it did not regrow hair and that their face looks younger.

Some reports are a wound or a scar rather than a complexion. #110 will not drop GHK-Cu after a forearm torn open on a bike chain closed in a way that surprised urgent care. #86 got nothing for hair in six months and says two surgery scars faded. #638 at about two months, new growth at the base of a toenail that had been damaged for thirty years. The rest of the nail is not fixed.

The null reports belong in the same list. #646 used it daily for about four months, for rosacea and facial scarring, and sees no meaningful change in skin or hair. #571 names GHK among many daily peptides over four months and says only CJC-1295 was noticeable. #265 had clear skin at four months and is explicit that BPC-157 was in the mix, so they cannot say which did it.

GHK-Cu side effects users report

The complaint that comes up most often is the injection. Not everyone gets it, and a few people are annoyed that they don't.

• —#379 — the first shot hurt immediately and the site stayed painful for more than two weeks. They are not repeating it.
• —#159 — GHK-Cu stings, and the sting lingers. MOTS-c and Cartalax are in the same sentence.
• —#514 — a morning injection ached all day. They moved it to before bed.
• —#415 — nothing for nine days, then a sore site.
• —#445 — fine at first. Weeks in, every injection left an angry, painful lump. Diluting, going slower, rotating sites, and warming the liquid did not stop it.
• —#398 and #365 — no sting at all. #398 has also been taking copper and zinc pills and wonders if that is why.
• —#316 — daily use, high concentration, layered on retinol and acids. The face broke down for a month.
• —#292 — three weeks of duller, more congested skin before a later change. The writer calls that stretch the "copper uglies."
• —#406 — an injection near the cheekbones, then what look like sun spots.
• —#767 — a couple of weeks of topical use. Unsure about the skin. Chin hairs went from a handful to about thirty.
• —#54 — meant 5 mg, injected 50 mg into a deltoid. Sore for a few days.

Is GHK-Cu safe?

GHK-Cu is not an approved drug, and this page does not call it safe. The reports include a dermatologist's compliment, a month of irritated skin, injection lumps, a tenfold dosing error that stayed a sore shoulder, and people who noticed nothing. One serious reaction does not belong on the GHK-Cu side of the ledger: #770 had metallic taste, itching, and vomiting, then a later episode of struggling to breathe. The writer first blamed GHK-Cu or IGF, threw those out, and then had the same reaction within seconds of tesamorelin. Breathing trouble is a reason to get emergency care. The confession does not end as a GHK-Cu diagnosis.

More side-effect threads: peptide side effects.

GHK-Cu dosage: what people report

Most GHK-Cu confessions never state a dose. They say "three weeks," "six months," or "every night." The figures that do appear are single reports, and several of them are blends or mistakes:

• —#567 — both subcutaneous and topical. The written schedule is 1 mg a day in week 1, 1.5 mg a day in weeks 2–4, and 2 mg a day in week 5. One person.
• —#697 — gut injections. The same confession says 2 mg every two days and 1 mg a day. It is not one figure.
• —#127 — 3 mg a day by injection did nothing for their hair. A topical did, within a month. They do not state the topical amount.
• —#316 — after a month of facial irritation from daily high-concentration use on top of retinol and acids, the writer says they would have started at 1–2%, a few times a week. That is a postscript, not a starting plan this page is repeating as advice.
• —#589 — a KLOW blend: 2.0 of GHK listed next to 400 mcg of BPC-157, TB-500, and KPV. Not GHK-Cu alone. The unit on the 2.0 is the writer's.
• —#54 — 50 mg injected, when they meant 5 mg. Intramuscular, deltoid, sore for a few days.
• —#730 — 4 mg put on a balding scalp once. No result is described.
• —#527 — an 80 mg KLOW vial split into pen cartridges, injected subcutaneously at 3 mg GHK-Cu alongside 600 mcg each of the other three compounds. They report no sting. A blend, one shot.
• —#624 — not a dose but a label problem: an "80 mg" KLOW vial sent for testing came back as 116 mg of GHK-Cu alone. Whatever the vial says, the amount in it may differ. See sourcing.

This is not a dosing recommendation.

GHK-Cu before and after: timelines in the reports

Nobody published photographs. The before-and-after material is the writer's clock, and the clocks do not match.

• —#511 — one week. Skin feels smoother. They are taking it for hair and are not sure they wanted the skin change.
• —#221 — three weeks. Skin, and a chin scar. Injected.
• —#292 — worse at three weeks, a turn at week six, denser skin at week twelve.
• —#316 — a month of broken-down skin after layering it on retinol and acids.
• —#386 — month one. Forehead lines, nails, hair growth. Subtle, in their words.
• —#256 — three months, subcutaneous. Grey hairs they had at 35, gone. They wish they had before-and-after pictures. This page does not.
• —#265 — four months to clear skin, with BPC-157 also in use.
• —#646 — about four months, daily. They wanted to be one of the before-and-afters. Skin and hair look the same.
• —#253 and #86 — six months. #253, topical: less shedding, thicker hair at the temples and hairline, brighter skin, alongside training and sleep changes. #86: hair unchanged, surgery scars faded.
• —#638 — about two months for a strip of new toenail growth. Thirty years of damage above that strip is still there.

Copper peptides for hair, stacks, and comparisons

Hair is a real subject of these reports, and the reports contradict each other. #253 at six months of topical use: less hair loss, thicker temples and hairline. #697 says a receding hairline filled in after a few months of gut injections, and dismisses topical use. The rest of that stack is retatrutide and MOTS-c. #633 describes hair growing back at a receding hairline and is also on retatrutide. #127 is the reverse of #697: topical use stopped shedding within a month, and 3 mg a day by injection had not. #103 says grey hair stopped and colour came back. #256 says grey hairs were gone at three months.

The other hair file is empty on purpose. #86 at six months: nothing for hair. #75 did not regrow hair. #646 at four months: hair the same. #767 grew more chin hair and is unsure about any scalp or skin benefit. A copper peptide for hair, in this archive, is a mixed set of stories, several of them stacked with other compounds.