Thymosin Beta-4

Full-length thymic protein from which TB-500 is derived. Coordinates actin dynamics in tissue repair, wound healing, and cardiac regeneration; the intact parent molecule of the TB-500 fragment.

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Also known as:

tb4thymosin b4full length tb4thymosin beta4

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Peptides for Recovery

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Community Q&A

What is the difference between Thymosin Beta-4 and TB-500?
Community accounts consistently describe TB-500 as a specific fragment of Thymosin Beta-4 — the Ac-SDKP tetrapeptide sequence that contains much of the healing activity. Full Thymosin Beta-4 is the complete 43-amino acid protein. Accounts from users who have tried both describe TB-500 as the more accessible and community-tested form; full TB4 accounts are rarer and describe similar healing outcomes with uncertainty about whether the additional sequence adds meaningful benefit over the fragment.
Why do people use TB-500 instead of Thymosin Beta-4?
Community accounts attribute the preference for TB-500 to practical factors: better availability, lower cost, and a larger body of community evidence from years of established use. Full Thymosin Beta-4 accounts describe sourcing challenges and higher expense. The therapeutic outcomes in community confessions are described as similar — most accounts frame TB-500 as capturing the clinically relevant portion of the parent molecule's activity.