Palmitoyl Tripeptide-1

Palmitoyl tripeptide-1 (Pal-GHK) that stimulates collagen production. Lipid modification enhances skin penetration; a component of Matrixyl 3000 alongside Palmitoyl Tetrapeptide-7.

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Also known as:

pal-ghkbiopeptide-clpalmitoyl-gly-his-lys

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Community Q&A

How does Palmitoyl Tripeptide-1 compare to GHK-Cu?
Community accounts distinguish the two: Palmitoyl Tripeptide-1 (Pal-GHK) lacks the copper ion, while GHK-Cu includes it. The copper chelation in GHK-Cu is described in accounts as adding wound healing, antimicrobial, and additional anti-aging mechanisms beyond the collagen signalling shared by both. Palmitoyl Tripeptide-1 appears in accounts as the lipid-linked topical delivery form — the palmitoyl group enables better skin penetration than unmodified GHK.
What does Palmitoyl Tripeptide-1 do?
Community accounts describe Palmitoyl Tripeptide-1 as a collagen synthesis stimulator — mimicking the collagen breakdown products that signal the dermis to produce new collagen. As part of Matrixyl 3000, most accounts cannot isolate its specific contribution from the Palmitoyl Tetrapeptide-7 component. Standalone use in custom formulations is described by DIY skincare users who separate the two Matrixyl 3000 components for targeted protocols.