MGF
Mechano growth factor, an IGF-1 splice variant expressed in response to mechanical stress. Studied for muscle repair and satellite cell activation.
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Also known as:
mechano growth factorigf-1ecpegylated mgfpeg-mgf
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Community Q&A
- What does MGF do for muscle?
- Community accounts describe MGF as a local muscle repair signal — acting on satellite cells at the site of mechanical damage rather than producing systemic effects. The most commonly described use: injection into a specific lagging muscle group shortly after training to accelerate local hypertrophy. Accounts that use it this way describe noticeably improved development in the targeted muscle over 4–8 weeks. MGF accounts are concentrated in bodybuilding-focused communities rather than recovery or longevity contexts.
- When do you inject MGF?
- Community convention is injection within 30–60 minutes of training, into or near the trained muscle group. The rationale given consistently in confessions: MGF has a short half-life and should be present during the post-exercise satellite cell activation window. Pegylated MGF (PEG-MGF) accounts describe more flexible timing due to its extended half-life, with some accounts using it days after training. Non-pegylated MGF accounts are strict about the post-workout window.